Study Design Flowchart

Answer a few questions about your research question and the tool recommends the right study design — with strengths, limitations, and examples.

Study design hierarchy

The evidence pyramid ranks study designs by their ability to minimise bias. Higher designs provide stronger causal evidence but require more resources.

Level Design Causal inference Best for Key measure
1Systematic Review / Meta-AnalysisHighestSummarising all evidence on a questionPooled OR, RR, MD
2Randomised Controlled Trial (RCT)Very highEvaluating treatment or intervention efficacyRR, ARR, NNT
3Cohort StudyModerate–highIncidence, risk factors, natural historyRR, Incidence Rate
4Case-Control StudyModerateRare diseases, multiple exposuresOdds Ratio
5Cross-Sectional StudyLowPrevalence, associations at a point in timePrevalence, PR
6Ecological StudyVery lowPopulation-level associations, hypothesis generationCorrelation
7Case Report / Case SeriesNoneRare conditions, adverse events, novel observationsDescriptive

Source: Sackett DL et al. Evidence Based Medicine. Churchill Livingstone, 1997. Reviewed Sep 2026.

For educational and research planning purposes. Study design selection in practice depends on many contextual factors including ethics, feasibility, funding, and local context. Consult a research methodologist for complex study designs.